EFFECT ANTYPIRETIC OF INFUSA THORN SPINACH LEAF ( Amaranthus Spinosus Linn.) AT WHITE MOUSE WISTAR GALUR

Thorn spinach (Amaranthus spinosus Linn.) is representing crop planted in many lawn

house. The usage of thorn spinach leaf is representing as antypiretic (anti fever). The intention of

this research isto prove effect of antypiretic (anti fever) of thorn spinach leaf and also compare

among infuse using dried leaf and fresh leaf.

In this researh has used 60 female white mouse tail, Wistar galur, age 3-4 months and

weight 150-200 gram. Mouse divided into 2 group which is the each group consist of 30 mouse

tail which then divided again in 6 unit which consist of 5 mouse tail. Each unit will get same

treatment that is: unit I represent control given treatment with aquadest 1 ml, unit II as comparator

given acetosal 1% with dose 45 mg/kg of BB per oral 1 ml, unit III, IV, V and of VI given each

thorn spinach leaf infuse with equivalent dose 0,25 g/kg of BB; 0,5 g/kg of BB;  1,0 g/kg of BB

and 2,0 g/kg of BB per oral. The treatment above give in 3 hour after every mouse injected with

pirogenic pepton 10% with 1 ml by intraperitoneal. Then 30 minut during 180 minute. The result

of this research is to be tested by  using one track variant analysis (ANAVA) and t test 95% trust

level.

 Best on T test, with dose infus wet and dray spinach leaf is compared given asetosal with

dose 45 mg/kg BB is wet infuse on V group with dose 1 g/Kg BB and dray infuse on VI group

with dose 2 g/kg BB. The presentation of effect antypiretic infuse based on AUC is shown on wet

infuse have the best result because doses is very little. 

Research by 
Lia Dahlia